RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions (IDR), reports a new study from the Institute of Science, Tokyo, Japan. Using ...

For decades, RNA was the overlooked ‘middle child’ of cellular molecules. DNA was celebrated as the blueprint of life, proteins carried out the work of the cell, and RNA was cast in a supporting role ...

RNA clusters (green colored) gradually disassemble within biomolecular condensates (magenta colored), returning the RNA to a soluble state. This occured after an antisense oligonucleotide engineered ...